前蛋白转化酶枯草溶菌素9(PCSK9)相关研究工具(蛋白、抗体)

Proprotein Convertase Subtilisin/Kexin type 9

PCSK9 Alternative Names

PCSK9, FH3, NARC1, LDLCQ1, NARC-1, HCHOLA3

PCSK9 Protein and Antibody

Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for proprotein convertase subtilisin/kexin type 9 (PCSK9) related research. Our antibody products include mouse monoclonal and rabbit polyclonal antibodies for application such as ELISA, Western Blotting, IHC, etc. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

PCSK9 Protein, Recombinant

Molecule	Species	Description	Cat No	Size/Price
PCSK9	Human	PCSK9 protein, Recombinant	10594-H08H	20μg($290); Order
PCSK9	Mouse	PCSK9 protein, Recombinant	50251-M08H	100μg($290); Order
PCSK9	Rhesus	PCSK9 protein, Recombinant	11054-K08H	20μg($290); Order

PCSK9 Antibody

Molecule	Application	Description	Cat No	Size/Price
Human PCSK9	WB, ELISA	Mouse Monoclonal Antibody	10594-MM01	200µg($95) 500µg($195) Order
Human PCSK9	WB	Rabbit Monoclonal Antibody	10594-RM03	100µg($190) 200µg($295) Order
Human PCSK9	WB, ELISA	Rabbit Polyclonal Antibody	10594-RP02	500µg($150) 1m($240) Order
Human PCSK9	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10594-RP04	100µg($250); Order

PCSK9 Related Areas

Enzymes >>Serine Proteases& Regulators>>Serine Proteases>>Proprotein Convertases>>PCSK9

PCSK9 Related Products

LDLR Protein

Molecule	Species	Description	Cat No	Size/Price
LDLR	Human	LDLR Protein, Recombinant	10231-H08H	50μg($300); Order
LDLR	Mouse	LDLR Protein, Recombinant	50305-M08H	50μg($300); Order

PCSK9 Background

Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

References