人表皮生长因子受体2(Her2)重组蛋白及抗体

HER2 Protein & Antibody (ErbB2, CD340)

Human Epidermal Growth Factor Receptor 2

HER2 Alternative Names

HER2, HER-2, ERBB2, CD340, NEU, NGL, TKR1, c-erbB-2, HER-2/neu [Homo sapiens]

HER2, HER-2, Erbb2, Erbb-2, RP23-355L10.8, Neu, c-erbB2, c-neu, mKIAA3023 [Mus musculus]

HER2 Protein & Antibody

Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for EGF related research. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

HER2 Protein, Recombinant

Molecule	Species	Description	Cat No	Size/Price
HER2/ErbB2	Human	HER2/ErbB2 Protein, Recombinant	10004-H08H	100µg($290);Order
HER2/ErbB2	Human	HER2/ErbB2/Fc Protein, Recombinant	10004-H02H	100µg($290);Order

HER2 Antibody

Molecule	Application	Description	Cat No	Size/Price
Human HER2/ErbB2	ELISA	Mouse Monoclonal Antibody	10004-MM01	200µg($95) 500µg($195) Order
Human HER2/ErbB2	WB	Mouse Monoclonal Antibody	10004-MM02	200µg($95) 500µg($195) Order
Human HER2/ErbB2	ELISA	Rabbit Polyclonal Antibody	10004-RP03	500µg($150) 1mg($240) Order
Human HER2/ErbB2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10004-RP04	100µg($250); Order

HER2 Related Areas

Cancer>>Cancer Biomarkers>>HER2/ErbB2

Cancer>>Growth Factor & Receptor>>EGF Family & Receptor>>HER2/ErbB2

Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>HER2/ErbB2

Immunology>>Cluster of Differentiation>>Other>>HER2/ErbB2/CD340

HER2 Related Products

EGF Receptor Family Protein

Molecule	Species	Protein
HER1	Human	HER1 Protein, Recombinant
HER1	Human	HER1/Fc Protein, Recombinant
HER3	Human	HER3/Fc Protein, Recombinant
HER4	Human	DAN/NBL1/Fc Protein, Recombinant

EGF Ligands Protein

Molecule	Species	Protein
EGF	Hunan	EGF/Fc Protein, Recombinant

EGF Receptor Family ORF Clone

Molecule	Species	ORF Clone
HER2	Human	Homo sapiens HER2 transcript variant 1 DNA ORF Clone(NM_004448.2)
HER3	Human	Homo sapiens HER3 transcript variant 1 DNA ORF Clone(NM_001982.2)
HER4	Human	Homo sapiens HER4 transcript variant JM-a/CVT-2 DNA ORF Clone(NM_001042599.1)

EGF Ligands ORF Clone

Molecule	Species	Protein
EGF-L6	Hunan	Homo sapiens EGF-L6 DNA ORF Clone(NM_015507.2)
Neurexophilin-1	Human	Homo sapiens Neurexophilin-1 DNA ORF Clone(NM_152745.2)

HER2 Background

Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a typeⅠmembrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.

HER2 Related Studies