酸性/碱性成纤维细胞生长因子(aFGF/bFGF)

aFGF Protein & Antibody

acidic Fibroblast Growth Factor

aFGF Alternative Names

AFGF, ECGF, ECGFA, ECGF-beta, ECGFB, FGF-1, FGF1, FGFA, FGF-alpha, GLIO703, HBGF1

aFGF Protein & Antibody

aFGF, also known as FGF-1, is a member of the fibroblast growth factor family. Sino Biological offers a comprehensive set of tools for FGF related research. These include recombinant proteins (high purity, human cell-expressed), antibodies, ELISA kits, and ORF clones. Our antibody products were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

aFGF Protein, Recombinant

Molecule	Species	Description	Cat No	Size/Price
aFGF	Human	aFGF protein, Recombinant	10013-HNAE	100µg ($150) 1mg ($880) 10mg ($6200) Order
aFGF	Mouse	aFGF protein, Recombinant	50179-MNAE	100µg ($150) 1mg ($880) 10mg ($6200) Order

  10013-HNAE:  ED₅₀ = 50 - 200 pg / ml. Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts.

aFGF Antibody

Molecule	Application	Description	Cat No	Size/Price
Human aFGF	WB, ELISA	Mouse Monoclonal Antibody	10013-MM01	200µg($95) 500µg($195) Order
Human aFGF	WB, ELISA	Rabbit Polyclonal Antibody	10013-RP02	500µg($150) 1mg($240) Order
Human aFGF	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10013-RP03	100μg($250); Order

aFGF Related Areas

Cancer>>Cancer Biomarkers>>aFGF

Cancer>>Growth Factor & Receptor>>FGF & Receptor>>aFGF

aFGF Related Products

Protein Products

Molecule	Species	Description
FGF2/bFGF	Human	bFGF Protein, Recombinant
FGF9	Human	FGF9/Fc Protein, Recombinant
FGF10	Human	FGF10 Protein, Recombinant
FGFR1	Human	FGFR1 Protein, Recombinant
FGFR1	Human	FGFR1/Fc Protein, Recombinant
FGFR2	Human	FGFR2/Fc Protein, Recombinant
FGFR3	Mouse	FGFR3/Fc Protein, Recombinant
FGFR4	Human	FGFR4/Fc Protein, Recombinant
FGFR4	Human	FGFR4/Fc Protein, Recombinant
FGFR4	Mouse	FGFR4 Protein, Recombinant
FGFR4	Mouse	FGFR4/Fc Protein, Recombinant

Antibody Products

Molecule	Application	Description
Human bFGF/FGF2	ELISA	Rabbit Polyclonal Antibody
Human bFGF/FGF2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse FGFR4	ELISA	Rabbit Polyclonal Antibody
Mouse FGFR4	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)

ORF Clone Products

Molecule	Species	Description
FGF2/bFGF	Human	Homo sapiens bFGF DNA ORF Clone(NM_002006.4)
FGF5	Human	Homo sapiens FGF5 transcript variant 1 DNA ORF Clone(NM_004464.3)
FGF7	Human	Homo sapiens FGF7/KGF DNA ORF Clone (NM_002009.2)
FGF9	Human	Homo sapiens FGF9 DNA ORF Clone(NM_002010.1)
FGF10	Human	Homo sapiens FGF10 DNA ORF Clone(NM_004465.1)
FGF12	Human	Homo sapiens FGF12 transcript variant 2 DNA ORF Clone(NM_004113.4)
FGF13	Human	Homo sapiens FGF13 DNA ORF Clone(NM_004114.2)
FGF14	Human	Homo sapiens FGF14 DNA ORF Clone(NM_004115.3)
FGF21	Human	Homo sapiens FGF21 DNA ORF Clone(NM_019113.2)

aFGF Background

aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.

References