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北京义翘神州科技股份有限公司(Sino Biological Inc.)
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神经生成因子(NGFB, beta-NGF)及相关研究工具
1579 人阅读发布时间：2010-05-05 15:48
NGF Protein (Nerve growth factor, NGFB, beta-NGF)
NGF Protein Products
| Molecule | Species | Description | Cat No | Size/Price |
| NGF / NGFB | Human | NGF Protein, Recombinant |
11050-HNAC | Order |
11050-HNAC: ED50 = 0.4 - 1.0 ng / ml. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.
All NGF Protein and Antibody
NGF Alternative Names
NGF, NGFB, Beta-NGF, HSAN5, MGC161426, MGC161428
NGF Related Areas
Cancer>>Growth Factor & Receptor>>Neurotrophin & Receptor>>NGF
NGF Protein Related Products
| Molecule | Species | Description |
| PD-ECGF | Human | PD-ECGF Protein, Recombinant |
| TPO/THPO | Human | TPO/THPO Protein, Recombinant |
| TPO/THPO | Mouse | TPO/THPO Protein, Recombinant |
| WISP1 | Human | WISP1 Protein, Recombinant |
| Molecule | Application | Description |
| Human |
WB, ELISA | Mouse Monoclonal Antibody |
| Human TPO/THPO |
ELISA | Rabbit Polyclonal Antibody |
| Human Thrombopoietin |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Mouse TPO/THPO |
ELISA | Rabbit Polyclonal Antibody |
| Mouse Thrombopoietin |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Molecule | Species | Description |
| EG-VEGF | Human | Homo sapiens EG-VEGF DNA ORF Clone(NM_032414.2) |
| HGF | Human | Homo sapiens HGF DNA ORF Clone(NM_000601.4) |
| NOV/CCN3 | Human | Homo sapiens NOV/CCN3 DNA ORF Clone(NM_002514.3) |
| PD-ECGF | Human | Homo sapiens PD-ECGF DNA ORF Clone(NM_001953.3) |
| TPO/THPO | Human | Homo sapiens TPO/THPO DNA ORF Clone(NM_000460.2) |
| WISP1 | Human | Homo sapiens WISP1 DNA ORF Clone(NM_003882.2) |
NGF Background
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
NGF Related Studies
- Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
- Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
- Xanthos DN, et al. (2009) The roles of nerve growth factor and cholecystokinin in the enhancement of morphine analgesia in a rodent model of central nervous system inflammation. Neuropharmacology. 56(3): 684-91.
- Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.